Bromelain and its anti-inflammatory therapeutic application in humans: a scope review.
DOI:
https://doi.org/10.12873/432martinezKeywords:
Bromelina, Nutrición, Uso clínico, Inflamación, antiinflamatorioAbstract
Pineapple is the common name for Ananas comosus Merr (syns. A. sativus, Ananassa sativa, Bromelia ananas, B. comosa), it has been used over time as a remedy to cure different diseases.
In vivo and in vitro studies have shown anti-inflammatory therapeutic efficacy through the elimination of molecules from the cell surface, a decrease in plasmakinin levels, a prostaglandin inhibitor, pro-inflammatory cytokines, in addition to increasing tissue permeability through fibrinolysis and promoting the reabsorption of edema fluid in the bloodstream.
In this review, articles on bromelain and its anti-inflammatory activity in humans are compiled, based on the criteria for reporting scoping reviews: PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analysis). Its objective is to describe therapeutic doses that have an anti-inflammatory effect in humans, the above could favor the reduction of hospital stay, symptoms and treatment costs.
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