Oral supplementation with a collagen milk product enhances skin elasticity in adult women: a randomized, placebo-controlled clinical trial

Dien Kurtanty; Prita Dhyani Swamilaksita; Harna; Mertien Sa'pang; Ade Heryana; Diah Mulyawati Utari

doi:10.12873/

Autores

Dien Kurtanty Department of Nutrition Science, Faculty of Health Sciences, Esa Unggul University.
Prita Dhyani Swamilaksita Department of Public Health, Faculty of Health Sciences, Esa Unggul University.
Harna Department of Public Health, Faculty of Health Sciences, Esa Unggul University.
Mertien Sa'pang Department of Nutrition Science, Faculty of Health Sciences, Esa Unggul University.
Ade Heryana Department of Nutrition Science, Faculty of Health Sciences, Esa Unggul University.
Diah Mulyawati Utari

DOI:

https://doi.org/10.12873/

Palavras-chave:

collagen-enriched milk, skin elasticity, dermal collagen, functional food, women

Resumo

Introduction: Skin aging is influenced by genetic, hormonal, environmental, and nutritional factors. Collagen, the main structural protein in the dermis, decreases with age, leading to reduced elasticity and firmness. Nutritional strategies such as oral collagen supplementation have been proposed to improve skin health. However, evidence from Southeast Asian populations, particularly Indonesian women, remains limited.

Methods: This randomized, placebo-controlled clinical trial involved 60 adult women aged 30–50 years in Bogor, Indonesia. Subjects were randomly assigned to receive either collagen-enriched milk or a placebo for eight weeks. Anthropometric parameters, nutrient intake, and collagen loss score were measured before and after intervention. Data were analyzed using paired and independent t-tests, followed by ANCOVA adjusted for age, BMI (p < 0.05).

Results: No significant changes were observed in body weight or BMI (p > 0.05), indicating no effect on energy balance. However, collagen loss significantly decreased in the intervention group (from 66.87 ± 16.0% to 57.53 ± 17.2%, p = 0.012), while remaining unchanged in the control group (p = 0.957). ANCOVA revealed a significant between-group difference (p = 0.042; η² = 0.051), suggesting a small-to-moderate effect of collagen milk on dermal collagen metabolism. Nutrient intake remained stable across both groups.

Conclusion: Eight weeks of collagen-enriched milk supplementation significantly improved dermal collagen integrity without altering nutritional status or energy intake. This supports the potential role of collagen-based functional foods in promoting skin health and delaying early aging among adult women.

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