Evaluation of an expert system for enteral nutritional support in critically ill patients with gastrointestinal dysfunction.

Authors

  • Diana TREJOS GALLEGO Nutricionista
  • Diego MELO SOLARTE
  • William NARVÁEZ SOLARTE
  • Clara Helena GONZÁLEZ CORREA

DOI:

https://doi.org/10.12873/421trejos-gallego

Keywords:

: biomedical technologies; intestinal failure; intestinal failure; mobile apps; critical care.

Abstract

Background: Medicine and nutrition have used computer tools to support decision-making that improves patient care. An expert system is one of these tools that can guide users in handling a specific problem. Adherence to clinical practice guidelines for the nutritional management of patients with gastrointestinal dysfunction optimizes the medical and nutritional treatment of critically ill patients, enabling their recovery. The use of an expert system that facilitates this adherence can improve the clinical outcome of patients.
Objective: To evaluate whether an expert system developed as a tool to improve the adherence of physicians to international guidelines and to support decision-making improves the management of nutritional support in patients with gastrointestinal dysfunction.
Methods: Between June 2020 and January 2021, medical information was collected from critically ill patients with gastrointestinal dysfunction at Hospital Santa Sofía de Caldas. The study consisted of two experimental treatments, one of patients treated with the help of the expert system and the other of patients treated without the help of the expert system, considered as a Control group. Data were collected during the first four months of the study, without the help of the expert system, and in the four subsequent months, nutritional care was supported with the use of the expert system.
Results: There was a statistically significant difference (p = 0.0001) between treatments in the caloric and protein goals variables, and start of enteral nutrition. The patients treated with the help of the expert system presented higher compliance with caloric and protein goals and a shorter start time for enteral nutrition.
Conclusions: the use of the expert system is associated with better adherence to the recommendations of international guidelines, improving tolerance and the provision of enteral nutritional support.

References

- Reintam Blaser A, Poeze M, Malbrain ML, Björck M, Oudemans-van StraatenHM, Starkopf J, Gastro-Intestinal Failure Trial Group. Gastrointestinalsymptoms during the first week of intensive care are associated with pooroutcome: a prospective multicentre study. Intensive Care Med. 2013; 39:899–909. doi: 10.1007/s00134-013-2831-1.

- Singer P, Pichard C, Heidegger CP, Wernerman J. Considering energydeficit in the intensive care unit. Curr Opin Clin Nutr Metab Care.2010; 13:170-176.

- Cahill NE, Dhaliwal R, Day AG, Jiang X, Heyland DK. Nutritiontherapy in the critical care setting: ¿what is “best achievable” practice? An international multicenter observational study. Crit Care Med.2010; 38:395-401. doi: 10.1016 / j. clnu.2020.04.023

- Yeh DD, Fuentes E, Quraishi SA, et al. Adequate nutrition may get youhome:effect of caloric/protein deficits on the discharge destination ofcritically ill surgical patients. J Parenter Enteral Nutr. 2016; 40:37-44. doi: 10.1177 / 0148607115585142

- Reintam Blaser A, Jakob SM, Starkopf J. Gastrointestinal failure inthe ICU. Curr Opin Crit Care. 2016; 22:128-141. doi: 10.1097 / MCC.0000000000000286

- Wang K, McIlroy K, Plank LD, Petrov MS, Windsor JA. Prevalence, outcomes, and management of enteral tube feeding intolerance. A retrospective cohort study in a tertiary center. J Parenter Enteral Nutr.2017; 41:959-967. doi: 10.1177 / 0148607115627142

- Chapman MJ, Nguyen NQ, Deane AM. Gastrointestinal dysmotility: evidence and clinical management. Curr Opin Clin Nutr Metab Care.2013; 16:209-216. doi: 10.1097 / MCO.0b013e32835c1fa5

- Goates S, Du K, Braunschweig CA, Arensberg MB. Economic Burden

of Disease-Associated Malnutrition at the State Level. PLoS One.2016; 11: e0161833. doi: 10.1371 / journal.pone.0161833

- Asrani VM, Brown A, Huang W, Bissett I, Windsor JA. Gastrointestinal Dysfunction in Critical Illness: A Review of Scoring Tools. JPEN J Parenter Enteral Nutr. 2020; 44:182-196. doi:10.1002/jpen.1679

- Reintam Blaser, A., Starkopf, J., Alhazzani, W., Berger, M. M., Casaer, M. P., Deane, A. M., et al. ESICM Working Group on Gastrointestinal Function, E. W. G. on G. Early enteral nutrition in critically ill patients: ESICM clinical practice guidelines. Intensive Care Medicine. 2017; 43, 380–398. doi: 10.1007/s00134-016-4665-0

- Abhari S, Safdari R, Azadbakht L, et al. A Systematic Review of Nutrition Recommendation Systems: With Focus on Technical Aspects. J Biomed Phys Eng. 2019; 9:591-602. doi:10.31661/jbpe. v0i0.1248

- Mahmood S, Hoffman L, Ali IA, Zhao YD, Chen A, Allen K. Smart Phone/Device Application to Improve Delivery of Enteral Nutrition in Adult Patients Admitted to the Medical Intensive Care Unit. NutrMetabInsights. 2019; 12:1178638818820299. doi:10.1177/117863881882029

- Singer, P., ReintamBlaser, A., Berger, M. M., Alhazzani, W., Calder, P. C., Casaer, et al. ESPEN Guideline ESPEN guideline on clinical nutrition in the intensive care unit. 2019, doi: 10.1016/j.clnu.2018.08.037

- Badaró S, Ibañez Leonardo Javier y Agüero Martín J. Expertos: Fundamentos, Metodologías y Aplicaciones. Sebastián. Ciencia y Tecnología, 13, 2013, pp. 349-364 ISSN 1850-0870. Disponible en: https://www.palermo.edu/ingenieria/pdf2014/13/CyT_13_24.pdf

- Trtovac D, Lee J. The Use of Technology in Identifying Hospital Malnutrition: ScopingReview. JMIR Med Inform. 2018; 6: e4. doi: 10.2196/medinform.7601.

- North JC, Jordan KC, Metos J, Hurdle JF. Nutrition Informatics Applications in Clinical Practice: a Systematic Review. AMIA Annu Symp Proc. 2015 Nov 5; 2015:963-72. PMID: 26958233 PMCID: PMC4765562

- Hamine S, Gerth-Guyette E, Faulx D, Green BB, Ginsburg AS. Impact of mHealth chronic disease management on treatment adherence and patient outcomes: a systematic review. J Med Internet Res. 2015; 17:e52. doi: 10.2196/jmir.3951.

- Reintam Blaser A, Preiser JC, Fruhwald S, Wilmer A, Wernerman J, Benstoem C, et al. Working Group on Gastrointestinal Function within the Section of Metabolism, Endocrinology and Nutrition (MEN Section) of ESICM. Gastrointestinal dysfunction in the critically ill: a systematic scoping review and research agenda proposed by the Section of Metabolism, Endocrinology and Nutrition of the European Society of Intensive Care Medicine. Crit Care. 2020 15; 24:224. doi: 10.1186/s13054-020-02889-4.

- Frantz DJ, McClave SA, Hurt RT, Miller K, Martindale RG. Cross-SectionalStudy of U.S. Interns' Perceptions of Clinical Nutrition Education. JPEN J Parenter Enteral Nutr. 2016; 40:529-35. doi: 10.1177/0148607115571016.

- Bernstam EV, Smith JW, Johnson TR. What is biomedical informatics? J Biomed Inform. 2010; 43:104-10. doi: 10.1016/j.jbi.2009.08.006.

- Pronovost PJ. Enhancing physicians' use of clinical guidelines. JAMA. 2013 18; 310:2501-2. doi: 10.1001/jama.2013.281334.

- McCoy AB, Waitman LR, Lewis JB, Wright JA, Choma DP, Miller RA. Et al. A framework for evaluating the appropriateness of clinical decision support alerts and responses. J Am Med Inform Assoc. 2012; 19:346-52. doi: 10.1136/amiajnl-2011-000185.

- Chu LF, Erlendson MJ, Sun JS, Alva HL, Clemenson AM. Mobile computing in medical education: opportunities and challenges. CurrOpin Anaesthesiol. 2012; 25:699-718. doi: 10.1097/ACO.0b013e32835a25f1.

- Taylor BE, McClave SA, Martindale RG, Warren MM, Johnson DR,Braunschweig C, et al. Guidelines for the provision and assessment ofnutrition support therapy in the adult critically ill patient: Society of CriticalCare Medicine (SCCM) and American Society for Parenteral and EnteralNutrition (A.S.P.E.N.). Crit Care Med. 2016; 44:390–438. doi:10.1097/CCM.0000000000001525

- Cederholm, T., Jensen, G. L., Correia, M., Gonzalez, M. C., Fukushima, R., Higashiguchi, T., et al. GLIM Working Group. GLIM criteria for the diagnosis of malnutrition - A consensus report from the global clinical nutrition community. Clinical nutrition. 2019 38, 1–9. doi: 10.1016/j.clnu.2018.08.002

- Enriquez-Sánchez LB, Carrillo-Gorena MJ, Granados-Aldaz LA, Balderrama-Miramontes LF, Gallegos-Portillo LG, RezaLeal CN, et al. Intestinal failure functional classification type associated with an extended length of stay at the intestinal failure unit, Central Hospital in Chihuahua, Mexico. Cir. 2019; 87:559-63. doi: 10.24875/CIRU.19000767.

- Fuglsang KA, Brandt CF, Scheike T, Jeppesen PB. Hospitalizations in patients with nonmalignant short-bowel syndrome receiving home parenteral support. Nutr Clin Pract. 2020; 35:894-902. doi: 10.1002/ncp.10471.

- Køhler M, Olesen SS, Rasmussen HH. Body composition predicts clinical outcome in patients with intestinal failure on long-term home parenteral nutrition. Clin Nutr ESPEN. 2018; 28:193-200. doi: 10.1016/j.clnesp.2018.08.004.

- Hay T, Bellomo R, Rechnitzer T. Constipation, diarrhea, and prophylactic

laxative bowel regimens in the critically ill: a systematic review and metaanalysis. J Crit Care. 2019; 52:242–50. doi: 10.1016/j.jcrc.2019.01.004.

- Perez-Calatayud AA, Carrillo-Esper R, Anica-Malagon ED, Briones-Garduño JC, Arch-Tirado E, Wise R, Malbrain MLNG. Point-of-care gastrointestinal and urinary tract sonography in daily evaluation of gastrointestinal dysfunction in critically ill patients (GUTS Protocol). Anaesthesiol Intensive Ther. 2018; 50:40–8. doi: 10.5603/AIT.a2017.0073.

- Lewis K, Alqahtani Z, McIntyre L, Almenawer S, Alshamsi F, Rhodes A, et al.The efficacy and safety of prokinetic agents in critically ill patients receivingenteral nutrition: a systematic review and meta-analysis of randomized trials.Crit Care. 2016; 20:259. doi: 10.1186/s13054-016-1441-z

- Deane AM, Lamontagne F, Dukes GE, Neil D, Vasist L, Barton ME, et al.Nutrition adequacy therapeutic enhancement in the critically ill: arandomized double-blind, placebo-controlled trial of the motilin receptoragonist camicinal (GSK962040): the NUTRIATE Study. JPEN J Parenter EnteralNutr. 2018; 42:949–59. doi: 10.1002/jpen.1038.

- Oczkowski SJW, Duan EH, Groen A, Warren D, Cook DJ. The use of bowelprotocols in critically ill adult patients: a systematic review and metaanalysis. Crit Care Med. 2017; 45: e718–26. doi: 10.1097/CCM.0000000000002315.

- Brigode WM, Jones C, Vazquez DE, Evans DC. Scrutinizing the evidence linking hypokalemia and ileus: a commentary on fact and dogma. Int JAcad Med. 2015; 1:21–6. Disponible en: https://www.ijam-web.org/text.asp?2015/1/1/21/172705

- Barletta JF, Asgeirsson T, Senagore AJ. Influence of intravenous opioid doseon postoperative ileus. Ann Pharmacother. 2011; 45:916–23. doi:10.1345/aph.1Q041.

- Rubinoff MJ, Piccione PR, Holt PR. Clonidine prolongs human small intestinetransit time: use of the lactulose-breath hydrogen test. Am J Gastroenterol.1989;84:372–4. PMID: 2929556

- Martos-Benítez FD, Gutiérrez-Noyola A, Soto-García A, González-Martínez I, Betancourt-Plaza I. Program of gastrointestinal rehabilitation and early postoperative enteral nutrition: a prospective study. Updates Surg. 2018; 70:105-112. doi: 10.1007 / s13304-018-0514-8

- Ricciardi R, Roberts PL, Read TE, Hall JF, Marcello PW, Schoetz DJ. Which adverse events are associated with mortality and prolonged length of stay following colorectal surgery? J GastrointestSurg. 2013; 17:1485-93. doi: 10.1007/s11605-013-2224-3.

- Karagozian R, Johannes RS, Sun X, Burakoff R. Increased mortality and length of stay among patients with inflammatory bowel disease and hospital-acquired infections. Clin Gastroenterol Hepatol. 2010; 8:961-5. doi: 10.1016/j.cgh.2010.07.017.

- Fuglsang KA, Brandt CF, Scheike T, Jeppesen PB. Hospitalizations in Patients with Non malignant Short-Bowel Syndrome Receiving Home Parenteral Support. Nutr Clin Pract. 2020;35(5):894-902. doi: 10.1002/ncp.10471.

Published

2022-03-29

How to Cite

TREJOS GALLEGO, D., MELO SOLARTE, D., NARVÁEZ SOLARTE, W., & GONZÁLEZ CORREA, C. H. (2022). Evaluation of an expert system for enteral nutritional support in critically ill patients with gastrointestinal dysfunction. Nutrición Clínica Y Dietética Hospitalaria, 42(01). https://doi.org/10.12873/421trejos-gallego

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