Association of Omega 3 and Omega 6 and Child Development: A Systematic Review


  • Fivi Melva Diana Department of Nutrition, Faculty of Public Health, Universitas Andalas
  • Najmiatul Fitria Department of Pharmacology and Clinical Therapy, Faculty of Pharmacy, Universitas Andalas, Padang, 25128, Indonesia


Palabras clave:

omega-3, omega-6, child development, systematic review


Introduction: Omega-3 and omega-6 long chain polyunsaturated fatty acids (LCPUFA) are the major components of structural central nervous system. This study aimed to summarize the relationship between omega-3 and/ or omega-6 LCPUFA on children development.

Method: Three large databases including Science Direct, Pubmed, and Cochrane were used to identify articles reporting the relationship of omega-3 and/or omega-6 and children development published between 2000 and 2021. The study was included if it was performed among under twelve children and provided the data of omega-3 and/ or omega-6 and cognitive development. This systematic review included both observational and experimental study. The publication bias was check using STROBE checklist.

Results: The result showed that 4 articles were included consisted of 3 observational studies and 1 experimental study. Two observational studies reported a significant association between omega-3 and/ or omega-6 and children development. However, the experimental study did not confirm these findings. Publications bias was observed in methodology, where the findings showed a weakness in generalizability.

Conclusion: This study concludes that omega-3 and omega-6 might play significant role in children development, but further study is needed to be done.


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Cómo citar

Diana, F. M., & Fitria, N. (2022). Association of Omega 3 and Omega 6 and Child Development: A Systematic Review. Nutrición Clínica Y Dietética Hospitalaria, 42(2).